※ PKA family introduction

    PKA (cAMP-dependent protein kinase) belongs to AGC group. PKA is characterized by its role as important downstream effecter of second messenger cAMP. PKA consists of multiple forms of regulatory and catalytic subunits and PKA holoenzyme contains two regulatory subunits and two catalytic subunits, which determines the biochemical and functional features. PKA keeps catalytically inactive under low levels of cAMP and PKA obtains its catalytic activity only after binding to the two binding sites on regulatory subunits. PKA involves in a varieties of cellular processes through phosphorylation of different nuclear and cytoplasmic substrates including metabolism, differentiation, synaptic transmission, ion channel activity, growth and development (1).

Reference
1. Feliciello, A., Gottesman, M.E. and Avvedimento, E.V. (2005) cAMP-PKA signaling to the mitochondria: protein scaffolds, mRNA and phosphatases. Cell Signal, 17, 279-287. PMID: 15567059

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Chr-0056	CHLREDRAFT_114555	A8II26	CHLREDRAFT_114555
2		iEKPD-Chr-0078	CHLREDRAFT_117219	A8IXU4	CHLREDRAFT_117219
3		iEKPD-Chr-0103	CHLREDRAFT_121355	A8JB50	CHLREDRAFT_121355
4		iEKPD-Chr-0254	CHLREDRAFT_153242	A8JDQ7	CHLRE_12g493250v5
5		iEKPD-Chr-0400	CHLREDRAFT_181974	Q695H0	CPKG1
6		iEKPD-Chr-0130	CHLREDRAFT_131695	A8J8T7	FAP295