Dasypus novemcinctus      AGC/PKC


※ PKC family introduction

    PKC (protein kinase C) belongs to AGC group. PKC can be grouped into three sections based on similar structural and activation requirements: classical, novel and atypical. Classical PKCs are activated by calcium, phosphatidylserine and diacylglycerol or phorbol esters. The novel PKCs lack a conserved region found in classical PKC and is activated by different lipids. The atypical PKCs is smallest in size in all PKCs which are activated by PS. PKCs keep an inactive state in the cytosol and translocate to the membrane vesicles, nuclear structures and cytoskeletal components after cell stimulation. Activated PKCs have been shown to involve in a varieties cellular processes including receptor desensitization, transcription, immune responses and cell growth (1).

Reference
1. Keenan, C. and Kelleher, D. (1998) Protein kinase C and the cytoskeleton. Cell Signal, 10, 225-232. PMID: 9617479


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dan-0089
ENSDNOG00000007274.3
2
iEKPD-Dan-1262
ENSDNOG00000007776.2
3
iEKPD-Dan-0118
ENSDNOG00000008880.3
4
iEKPD-Dan-1266
ENSDNOG00000011106.3
5
iEKPD-Dan-0193
ENSDNOG00000014971.3
6
iEKPD-Dan-0195
ENSDNOG00000015214.3
7
iEKPD-Dan-0461
ENSDNOG00000048651.1
8
iEKPD-Dan-0114
ENSDNOG00000008416.2
C3PT96
PRKCG
9
iEKPD-Dan-g005
ENSDNOG00000045814.1
C3PT95
PRKCG