Ficedula albicollis      AGC/PKC


※ PKC family introduction

    PKC (protein kinase C) belongs to AGC group. PKC can be grouped into three sections based on similar structural and activation requirements: classical, novel and atypical. Classical PKCs are activated by calcium, phosphatidylserine and diacylglycerol or phorbol esters. The novel PKCs lack a conserved region found in classical PKC and is activated by different lipids. The atypical PKCs is smallest in size in all PKCs which are activated by PS. PKCs keep an inactive state in the cytosol and translocate to the membrane vesicles, nuclear structures and cytoskeletal components after cell stimulation. Activated PKCs have been shown to involve in a varieties cellular processes including receptor desensitization, transcription, immune responses and cell growth (1).

Reference
1. Keenan, C. and Kelleher, D. (1998) Protein kinase C and the cytoskeleton. Cell Signal, 10, 225-232. PMID: 9617479


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Fia-0075
ENSFALG00000002418.1
U3JIA8
PRKCA
2
iEKPD-Fia-0122
ENSFALG00000003691.1
U3JM87
PRKCB
3
iEKPD-Fia-1094
ENSFALG00000003460.1
U3JLI1
PRKCD
4
iEKPD-Fia-0380
ENSFALG00000012934.1
U3KES8
PRKCE
5
iEKPD-Fia-0106
ENSFALG00000003419.1
U3JLA6
PRKCH
6
iEKPD-Fia-0266
ENSFALG00000008601.1
U3K1R8
PRKCI
7
iEKPD-Fia-1090
ENSFALG00000001793.1
U3JGG1
PRKCQ
8
iEKPD-Fia-0290
ENSFALG00000009477.1
U3K4C5
PRKCZ