Gorilla gorilla      AGC/PKC


※ PKC family introduction

    PKC (protein kinase C) belongs to AGC group. PKC can be grouped into three sections based on similar structural and activation requirements: classical, novel and atypical. Classical PKCs are activated by calcium, phosphatidylserine and diacylglycerol or phorbol esters. The novel PKCs lack a conserved region found in classical PKC and is activated by different lipids. The atypical PKCs is smallest in size in all PKCs which are activated by PS. PKCs keep an inactive state in the cytosol and translocate to the membrane vesicles, nuclear structures and cytoskeletal components after cell stimulation. Activated PKCs have been shown to involve in a varieties cellular processes including receptor desensitization, transcription, immune responses and cell growth (1).

Reference
1. Keenan, C. and Kelleher, D. (1998) Protein kinase C and the cytoskeleton. Cell Signal, 10, 225-232. PMID: 9617479


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Gog-0383
ENSGGOG00000015929.3
G3RIN3
PRKCA
2
iEKPD-Gog-0245
ENSGGOG00000010971.3
G3R5W0
PRKCB
3
iEKPD-Gog-1293
ENSGGOG00000003207.3
G3QL13
PRKCD
4
iEKPD-Gog-0277
ENSGGOG00000011965.3
G3R8H1
PRKCE
5
iEKPD-Gog-0295
ENSGGOG00000012604.3
A0A2I2YKG4
PRKCG
6
iEKPD-Gog-0189
ENSGGOG00000008357.3
G3QZ70
PRKCH
7
iEKPD-Gog-0235
ENSGGOG00000010639.3
G3R515
PRKCI
8
iEKPD-Gog-1318
ENSGGOG00000013552.3
G3RCJ3
PRKCQ
9
iEKPD-Gog-0309
ENSGGOG00000013021.4
G3RB70
PRKCZ