Poecilia formosa      AGC/PKC


※ PKC family introduction

    PKC (protein kinase C) belongs to AGC group. PKC can be grouped into three sections based on similar structural and activation requirements: classical, novel and atypical. Classical PKCs are activated by calcium, phosphatidylserine and diacylglycerol or phorbol esters. The novel PKCs lack a conserved region found in classical PKC and is activated by different lipids. The atypical PKCs is smallest in size in all PKCs which are activated by PS. PKCs keep an inactive state in the cytosol and translocate to the membrane vesicles, nuclear structures and cytoskeletal components after cell stimulation. Activated PKCs have been shown to involve in a varieties cellular processes including receptor desensitization, transcription, immune responses and cell growth (1).

Reference
1. Keenan, C. and Kelleher, D. (1998) Protein kinase C and the cytoskeleton. Cell Signal, 10, 225-232. PMID: 9617479


There are 13 genes.  Reviewed (0 or Unreviewed (13

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pof-0022
ENSPFOG00000000695.2
A0A087X4U3
2
iEKPD-Pof-0048
ENSPFOG00000001747.1
A0A087X7G7
3
iEKPD-Pof-0084
ENSPFOG00000003197.2
A0A087XC19
4
iEKPD-Pof-1630
ENSPFOG00000004121.2
A0A087XFF2
5
iEKPD-Pof-0133
ENSPFOG00000005126.2
A0A096M3V0
6
iEKPD-Pof-0162
ENSPFOG00000006014.2
A0A087XKR7
7
iEKPD-Pof-0234
ENSPFOG00000008240.2
A0A096LSS0
8
iEKPD-Pof-0264
ENSPFOG00000009188.2
A0A087XV30
9
iEKPD-Pof-0295
ENSPFOG00000010318.2
A0A087XXP0
10
iEKPD-Pof-0301
ENSPFOG00000010576.2
A0A087XXU6
11
iEKPD-Pof-0390
ENSPFOG00000013625.2
A0A087Y7K1
12
iEKPD-Pof-0413
ENSPFOG00000014668.1
A0A087Y9Q9
13
iEKPD-Pof-0033
ENSPFOG00000001134.2
A0A087X5V6
PRKCE