※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (14) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Aet-1186	F775_21726	M8C230	4327129
2		iEKPD-Aet-0212	F775_05197	M8C0V2	F775_05197
3		iEKPD-Aet-0216	F775_05236	R7WA66	F775_05236
4		iEKPD-Aet-0242	F775_05991	M8BBT6	F775_05991
5		iEKPD-Aet-0546	F775_11864	M8BWJ9	F775_11864
6		iEKPD-Aet-0559	F775_12146	M8BTU9	F775_12146
7		iEKPD-Aet-0799	F775_15836	R7WCG8	F775_15836
8		iEKPD-Aet-1042	F775_19575	M8BUA0	F775_19575
9		iEKPD-Aet-1167	F775_21348	M8BSL1	F775_21348
10		iEKPD-Aet-1459	F775_26462	M8CCN8	F775_26462
11		iEKPD-Aet-1515	F775_28279	M8BM97	F775_28279
12		iEKPD-Aet-1536	F775_29217	R7WBD9	F775_29217
13		iEKPD-Aet-1573	F775_30386	N1R228	F775_30386
14		iEKPD-Aet-1604	F775_31551	M8BAX2	F775_31551