Anolis carolinensis      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Anc-0344
ENSACAG00000014143.3
H9GL64
2
iEKPD-Anc-0453
ENSACAG00000023067.1
H9GUU8
3
iEKPD-Anc-0314
ENSACAG00000013019.3
H9GJH8
LOC100553094
4
iEKPD-Anc-0405
ENSACAG00000016599.3
H9GND5
RPS6KA1
5
iEKPD-Anc-0306
ENSACAG00000012681.3
G1KN36
RPS6KA3
6
iEKPD-Anc-0380
ENSACAG00000015587.3
H9GML6
RPS6KA4
7
iEKPD-Anc-0235
ENSACAG00000009878.2
G1KJL7
RPS6KA5
8
iEKPD-Anc-0311
ENSACAG00000012931.2
H9GJI7
RPS6KB1
9
iEKPD-Anc-0188
ENSACAG00000008242.3
G1KHN2
RPS6KB2