Astyanax mexicanus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Asm-0049
ENSAMXG00000001681.1
W5K2A4
2
iEKPD-Asm-0059
ENSAMXG00000002047.1
W5K3C4
3
iEKPD-Asm-0063
ENSAMXG00000002148.1
W5K3N1
4
iEKPD-Asm-0126
ENSAMXG00000004056.1
W5K996
5
iEKPD-Asm-0203
ENSAMXG00000006840.1
W5KHG0
6
iEKPD-Asm-0204
ENSAMXG00000006842.1
W5KHG3
7
iEKPD-Asm-0287
ENSAMXG00000009127.1
W5KP65
8
iEKPD-Asm-0414
ENSAMXG00000013462.1
W5L214
9
iEKPD-Asm-0425
ENSAMXG00000013900.1
W5L389