Callithrix jacchus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Caj-0209
ENSCJAG00000009919.2
F7G9C5
RPS6KA1
2
iEKPD-Caj-0114
ENSCJAG00000005239.2
F7GWP8
RPS6KA3
3
iEKPD-Caj-0385
ENSCJAG00000017957.2
F6RZV0
RPS6KA4
4
iEKPD-Caj-0177
ENSCJAG00000008317.2
F6RGA6
RPS6KA6
5
iEKPD-Caj-0028
ENSCJAG00000001416.2
F6ZZT2
RPS6KB1
6
iEKPD-Caj-0016
ENSCJAG00000000967.3
F7CC19
RPS6KB2