Cavia porcellus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Cap-0091
ENSCPOG00000003945.4
A0A286XCG0
RPS6KA1
2
iEKPD-Cap-0201
ENSCPOG00000008719.4
A0A286XBX2
RPS6KA3
3
iEKPD-Cap-0020
ENSCPOG00000000740.4
H0UUL4
RPS6KA4
4
iEKPD-Cap-0349
ENSCPOG00000015065.4
H0VSH3
RPS6KA5
5
iEKPD-Cap-0338
ENSCPOG00000014732.4
H0VRQ0
RPS6KB1
6
iEKPD-Cap-0240
ENSCPOG00000010518.4
A0A286XEH1
RPS6KB2