Chlorocebus sabaeus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Chs-0013
ENSCSAG00000000978.1
A0A0D9S842
RPS6KA1
2
iEKPD-Chs-0361
ENSCSAG00000014553.1
A0A0D9RPY4
RPS6KA3
3
iEKPD-Chs-0153
ENSCSAG00000007216.1
A0A0D9R4E4
RPS6KA4
4
iEKPD-Chs-0253
ENSCSAG00000010555.1
A0A0D9RDU5
RPS6KA6
5
iEKPD-Chs-0129
ENSCSAG00000005890.1
A0A0D9R0Q9
RPS6KB1
6
iEKPD-Chs-0203
ENSCSAG00000008598.1
A0A0D9R8B9
RPS6KB2