Danio rerio      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 8 genes.  Reviewed (1 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dar-0259
ENSDARG00000037574.7
Q6PFQ0
rps6ka6
2
iEKPD-Dar-0233
ENSDARG00000033437.10
F1QYQ1
rps6ka1
3
iEKPD-Dar-0248
ENSDARG00000035556.6
A0A0R4ID09
rps6ka3a
4
iEKPD-Dar-0379
ENSDARG00000057927.6
E7F469
rps6ka3b
5
iEKPD-Dar-0300
ENSDARG00000044436.7
A0A0R4IT22
rps6ka4
6
iEKPD-Dar-0415
ENSDARG00000060551.5
E7FE05
rps6ka5
7
iEKPD-Dar-0140
ENSDARG00000018399.9
E9QG10
rps6kb1a
8
iEKPD-Dar-0381
ENSDARG00000058230.4
F1R3V1
rps6kb1b