※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (6) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Dan-0035	ENSDNOG00000002501.3
2		iEKPD-Dan-0039	ENSDNOG00000003310.3
3		iEKPD-Dan-0247	ENSDNOG00000018560.3
4		iEKPD-Dan-0394	ENSDNOG00000041769.1
5		iEKPD-Dan-0452	ENSDNOG00000047970.1
6		iEKPD-Dan-0297	ENSDNOG00000032856.1	C3PT42	RPS6KA4