Dioscorea rotundata      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 14 genes.  Reviewed (0 or Unreviewed (14

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dir-0015
Dr00509
2
iEKPD-Dir-0237
Dr04529
3
iEKPD-Dir-0243
Dr04735
4
iEKPD-Dir-0249
Dr04887
5
iEKPD-Dir-0303
Dr06357
6
iEKPD-Dir-0359
Dr07445
7
iEKPD-Dir-0522
Dr10865
8
iEKPD-Dir-0568
Dr11949
9
iEKPD-Dir-0586
Dr12916
10
iEKPD-Dir-0588
Dr13015
11
iEKPD-Dir-0621
Dr13659
12
iEKPD-Dir-0626
Dr13874
13
iEKPD-Dir-0641
Dr14191
14
iEKPD-Dir-0714
Dr16943