Dipodomys ordii      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dio-0255
ENSDORG00000011494.2
A0A1S3GTL4
LOC106001479
2
iEKPD-Dio-0159
ENSDORG00000007779.2
A0A1S3FTT2
Rps6ka2
3
iEKPD-Dio-0261
ENSDORG00000011802.2
A0A1S3FZC8
Rps6ka3
4
iEKPD-Dio-0156
ENSDORG00000007519.2
A0A1S3FJ65
Rps6ka4
5
iEKPD-Dio-0179
ENSDORG00000008579.2
A0A1S3FX95
Rps6ka6
6
iEKPD-Dio-0328
ENSDORG00000014540.2
A0A1S3FJT9
Rps6kb2