Felis catus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Fec-0243
ENSFCAG00000012813.4
A0A2I2UPE2
RPS6KA1
2
iEKPD-Fec-0106
ENSFCAG00000005103.4
M3W3H1
RPS6KA2
3
iEKPD-Fec-0203
ENSFCAG00000010795.4
A0A2I2U9Z1
RPS6KA3
4
iEKPD-Fec-0009
ENSFCAG00000000512.4
A0A2I2V513
RPS6KA4
5
iEKPD-Fec-0172
ENSFCAG00000009130.4
A0A2I2UKC8
RPS6KA6
6
iEKPD-Fec-0332
ENSFCAG00000023434.2
M3X5V6
RPS6KB1
7
iEKPD-Fec-0067
ENSFCAG00000003395.4
M3W099
RPS6KB2