Gadus morhua      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Gam-0025
ENSGMOG00000000851.1
2
iEKPD-Gam-0071
ENSGMOG00000002350.1
3
iEKPD-Gam-0127
ENSGMOG00000004036.1
4
iEKPD-Gam-0139
ENSGMOG00000004426.1
5
iEKPD-Gam-0148
ENSGMOG00000004569.1
6
iEKPD-Gam-0277
ENSGMOG00000008995.1
7
iEKPD-Gam-0379
ENSGMOG00000012056.1
8
iEKPD-Gam-0386
ENSGMOG00000012269.1
9
iEKPD-Gam-0389
ENSGMOG00000012317.1