Gallus gallus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (2 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Gag-0367
ENSGALG00000037136.1
P18652
RPS6KA
2
iEKPD-Gag-0309
ENSGALG00000030580.1
Q5F3L1
RPS6KA5
3
iEKPD-Gag-0257
ENSGALG00000016406.5
A0A1D5PTW8
4
iEKPD-Gag-0316
ENSGALG00000031471.2
A0A1D5PEW0
5
iEKPD-Gag-0103
ENSGALG00000007097.5
E1C7L2
RPS6KA6
6
iEKPD-Gag-0070
ENSGALG00000005198.3
F1P4J0
RPS6KB1
7
iEKPD-Gag-0320
ENSGALG00000031629.1
A0A1D5PLD0
RPS6KB2