Gasterosteus aculeatus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Gaa-0204
ENSGACG00000007027.1
G3NVF0
2
iEKPD-Gaa-0331
ENSGACG00000011310.1
G3PBH5
3
iEKPD-Gaa-0376
ENSGACG00000012811.1
G3PH63
4
iEKPD-Gaa-0464
ENSGACG00000016035.1
G3PU77
5
iEKPD-Gaa-0474
ENSGACG00000016324.1
G3PVB1
6
iEKPD-Gaa-0525
ENSGACG00000018545.1
G3Q3R1
7
iEKPD-Gaa-0560
ENSGACG00000020215.1
G3Q9Y7
8
iEKPD-Gaa-0562
ENSGACG00000020273.1
G3QA73