Gorilla gorilla      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Gog-0435
ENSGGOG00000024860.2
G3RTE9
2
iEKPD-Gog-0479
ENSGGOG00000043275.1
A0A2I2Z0I0
3
iEKPD-Gog-0065
ENSGGOG00000002930.3
G3QKB5
RPS6KA1
4
iEKPD-Gog-0199
ENSGGOG00000008837.3
G3R0F8
RPS6KA3
5
iEKPD-Gog-0395
ENSGGOG00000016474.3
G3RK25
RPS6KA6
6
iEKPD-Gog-0220
ENSGGOG00000009999.3
G3R3D8
RPS6KB2