Ictidomys tridecemlineatus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ict-0098
ENSSTOG00000004355.3
A0A287DD79
RPS6KA1
2
iEKPD-Ict-0230
ENSSTOG00000010494.3
I3MFL8
RPS6KA3
3
iEKPD-Ict-0418
ENSSTOG00000026269.2
A0A287CSB8
RPS6KA4
4
iEKPD-Ict-0251
ENSSTOG00000011825.3
A0A287D7D6
RPS6KA5
5
iEKPD-Ict-0053
ENSSTOG00000002290.3
A0A287DD71
RPS6KA6
6
iEKPD-Ict-0422
ENSSTOG00000026687.2
I3N8P3
RPS6KB1
7
iEKPD-Ict-0413
ENSSTOG00000026088.2
I3MWZ8
RPS6KB2