Latimeria chalumnae      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Lac-0145
ENSLACG00000005654.1
H3A9Q1
2
iEKPD-Lac-0189
ENSLACG00000007348.1
H3AF81
3
iEKPD-Lac-0247
ENSLACG00000009732.1
H3AN37
LOC102365858
4
iEKPD-Lac-0193
ENSLACG00000007521.1
H3AFS7
RPS6KA1
5
iEKPD-Lac-0276
ENSLACG00000010571.1
H3AQU0
RPS6KA4
6
iEKPD-Lac-0297
ENSLACG00000011467.1
H3ATP4
RPS6KA5
7
iEKPD-Lac-0308
ENSLACG00000011872.1
H3AV14
RPS6KB1