Lepisosteus oculatus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Leo-0014
ENSLOCG00000001071.1
W5LYJ8
2
iEKPD-Leo-0080
ENSLOCG00000003638.1
W5M7H5
3
iEKPD-Leo-0087
ENSLOCG00000003823.1
W5M868
4
iEKPD-Leo-0124
ENSLOCG00000005457.1
W5MDY7
5
iEKPD-Leo-0177
ENSLOCG00000007090.1
W5MJN0
6
iEKPD-Leo-0380
ENSLOCG00000014006.1
W5N9G8
7
iEKPD-Leo-0424
ENSLOCG00000015032.1
W5ND05