Loxodonta africana      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Loa-0004
ENSLAFG00000000120.3
G3UN48
2
iEKPD-Loa-0093
ENSLAFG00000004940.3
G3SV84
RPS6KA1
3
iEKPD-Loa-0151
ENSLAFG00000007020.3
G3SZB4
RPS6KA3
4
iEKPD-Loa-0189
ENSLAFG00000008921.3
G3T2S4
RPS6KA4
5
iEKPD-Loa-0167
ENSLAFG00000007777.3
G3T0M1
RPS6KA6
6
iEKPD-Loa-0290
ENSLAFG00000014259.3
G3TCW7
RPS6KB1
7
iEKPD-Loa-0191
ENSLAFG00000008925.4
G3T2S5
RPS6KB2