Macaca fascicularis      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Maf-0422
ENSMFAG00000043523.1
2
iEKPD-Maf-0166
ENSMFAG00000031507.1
G7PP77
EGM_05368
3
iEKPD-Maf-0263
ENSMFAG00000036152.1
G7PPR5
EGM_05472
4
iEKPD-Maf-0453
ENSMFAG00000045085.1
G7Q2C5
EGM_18609
5
iEKPD-Maf-0471
ENSMFAG00000045848.1
G7Q356
EGM_18953
6
iEKPD-Maf-0449
ENSMFAG00000044982.1
G8F2H3
EGM_20832