※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (9) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mel-0060	MELLADRAFT_33818	F4RBH6	MELLADRAFT_33818
2		iEKPD-Mel-0065	MELLADRAFT_35870	F4RL45	MELLADRAFT_35870
3		iEKPD-Mel-0068	MELLADRAFT_37779	F4RUY8	MELLADRAFT_37779
4		iEKPD-Mel-0071	MELLADRAFT_38934	F4S0H9	MELLADRAFT_38934
5		iEKPD-Mel-0077	MELLADRAFT_40213	F4S716	MELLADRAFT_40213
6		iEKPD-Mel-0093	MELLADRAFT_47456	F4RDA6	MELLADRAFT_47456
7		iEKPD-Mel-0160	MELLADRAFT_91112	F4R769	MELLADRAFT_91112
8		iEKPD-Mel-0175	MELLADRAFT_94122	F4S6J6	MELLADRAFT_94122
9		iEKPD-Mel-0178	MELLADRAFT_94327	F4S7B2	MELLADRAFT_94327