Meleagris gallopavo      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Meg-0237
ENSMGAG00000009480.1
H9H1L4
RPS6KA1
2
iEKPD-Meg-0311
ENSMGAG00000012309.2
G1NI96
RPS6KA2
3
iEKPD-Meg-0380
ENSMGAG00000014663.2
G1NP91
RPS6KA3
4
iEKPD-Meg-0331
ENSMGAG00000013061.2
G3UR38
RPS6KA5
5
iEKPD-Meg-0118
ENSMGAG00000004748.1
G1MZX0
RPS6KA6
6
iEKPD-Meg-0188
ENSMGAG00000007416.1
G1N6A7
RPS6KB1
7
iEKPD-Meg-0106
ENSMGAG00000004389.2
H9H0P4
RPS6KB2