Mesocricetus auratus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Mea-0344
ENSMAUG00000017784.1
A0A1U7R554
Rps6ka1
2
iEKPD-Mea-0280
ENSMAUG00000015390.1
A0A1U7QTC0
Rps6ka3
3
iEKPD-Mea-0252
ENSMAUG00000014157.1
A0A1U7QBA2
Rps6ka4
4
iEKPD-Mea-0251
ENSMAUG00000014082.1
A0A1U7QL93
Rps6ka5
5
iEKPD-Mea-0031
ENSMAUG00000001357.1
A0A1U7RAD2
Rps6ka6
6
iEKPD-Mea-0327
ENSMAUG00000017230.1
A0A1U7QBH7
Rps6kb2