※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (7) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mim-0075	ENSMICG00000004111.3
2		iEKPD-Mim-0076	ENSMICG00000004112.3
3		iEKPD-Mim-0123	ENSMICG00000006433.3
4		iEKPD-Mim-0153	ENSMICG00000007848.3
5		iEKPD-Mim-0157	ENSMICG00000007960.3
6		iEKPD-Mim-0369	ENSMICG00000029334.2
7		iEKPD-Mim-0405	ENSMICG00000035191.2