Mustela putorius furo      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Muf-0090
ENSMPUG00000003384.1
M3XWA4
2
iEKPD-Muf-0389
ENSMPUG00000015702.1
M3YW83
RPS6KA1
3
iEKPD-Muf-0159
ENSMPUG00000006452.1
M3Y4Z6
RPS6KA2
4
iEKPD-Muf-0323
ENSMPUG00000012899.1
M3YN93
RPS6KA4
5
iEKPD-Muf-0156
ENSMPUG00000006292.1
M3Y4I7
RPS6KA6
6
iEKPD-Muf-0379
ENSMPUG00000015180.1
M3YUR1
RPS6KB1
7
iEKPD-Muf-0107
ENSMPUG00000003899.1
M3XXR8
RPS6KB2