Myotis lucifugus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Myl-0423
ENSMLUG00000022302.1
G1QEZ1
2
iEKPD-Myl-0449
ENSMLUG00000026476.1
G1Q7Q1
3
iEKPD-Myl-0295
ENSMLUG00000012980.2
G1PLR9
RPS6KA3
4
iEKPD-Myl-0360
ENSMLUG00000015440.2
G1PSD7
RPS6KA6
5
iEKPD-Myl-0086
ENSMLUG00000003666.2
G1P0P8
RPS6KB1
6
iEKPD-Myl-0113
ENSMLUG00000005128.2
G1P418
RPS6KB2