※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (16) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Nia-0455	A4A49_31702	A0A1J6K637	A4A49_31702
2		iEKPD-Nia-0096	A4A49_05419	A0A1J6I6G1	AGC1-5
3		iEKPD-Nia-0077	A4A49_04413	A0A1J6I8A3	AGC1-7_1
4		iEKPD-Nia-0588	A4A49_38999	A0A1J6JS75	D6PKL1
5		iEKPD-Nia-0293	A4A49_21970	A0A1J6INQ0	D6PKL2_0
6		iEKPD-Nia-0073	A4A49_04082	A0A1J6IXA6	D6PKL2_1
7		iEKPD-Nia-0004	A4A49_00270	A0A1J6IRE6	D6PKL2_2
8		iEKPD-Nia-0440	A4A49_30646	A0A1J6KKX2	D6PKL2_4
9		iEKPD-Nia-0629	A4A49_43345	A0A1J6JNI6	D6PKL2_5
10		iEKPD-Nia-0480	A4A49_33490	A0A1J6KFT8	KIPK_0
11		iEKPD-Nia-0224	A4A49_16253	A0A1J6IWG1	KIPK_1
12		iEKPD-Nia-0525	A4A49_35932	A0A1J6JVF0	KIPK_3
13		iEKPD-Nia-0504	A4A49_34903	A0A1J6J952	KPK1_1
14		iEKPD-Nia-0385	A4A49_27305	A0A1J6KIB5	OXI1
15		iEKPD-Nia-0289	A4A49_21755	A0A1J6I737	UCNL
16		iEKPD-Nia-0563	A4A49_37544	A0A1J6JS73	WAG1