Nomascus leucogenys      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Nol-0225
ENSNLEG00000009314.3
G1RDR9
RPS6KA1
2
iEKPD-Nol-0242
ENSNLEG00000009925.3
G1RFU1
RPS6KA3
3
iEKPD-Nol-0133
ENSNLEG00000005042.3
A0A2I3GXP5
RPS6KA4
4
iEKPD-Nol-0074
ENSNLEG00000002544.3
G1QQD9
RPS6KA6
5
iEKPD-Nol-0021
ENSNLEG00000000636.2
G1QIR2
RPS6KB1
6
iEKPD-Nol-0164
ENSNLEG00000006392.3
G1R3K4
RPS6KB2