※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (10) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Ora-0096	ENSOANG00000004152.2	F6Z908
2		iEKPD-Ora-0370	ENSOANG00000015078.2	F6PQK5
3		iEKPD-Ora-0375	ENSOANG00000015363.2	F7B9C0
4		iEKPD-Ora-0406	ENSOANG00000021243.2	F6YCZ3
5		iEKPD-Ora-0451	ENSOANG00000029646.1	K7EFA2
6		iEKPD-Ora-0467	ENSOANG00000030776.1	K7E7W1
7		iEKPD-Ora-0475	ENSOANG00000031451.1	K7E8X4
8		iEKPD-Ora-0388	ENSOANG00000019835.2	F6WS32	LOC100077729
9		iEKPD-Ora-0253	ENSOANG00000010658.2	F6V2V1	RPS6KA3
10		iEKPD-Ora-0044	ENSOANG00000002226.3	F6TPX7	RPS6KB1