Ovis aries      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ova-0103
ENSOARG00000004384.1
W5P2Q3
RPS6KA1
2
iEKPD-Ova-0111
ENSOARG00000004895.1
W5P4A1
RPS6KA2
3
iEKPD-Ova-0170
ENSOARG00000007576.1
W5PCG8
RPS6KA4
4
iEKPD-Ova-0087
ENSOARG00000003572.1
W5P069
RPS6KA5
5
iEKPD-Ova-0042
ENSOARG00000001699.1
W5NUE2
RPS6KA6
6
iEKPD-Ova-0329
ENSOARG00000014401.1
W5PYC2
RPS6KB1
7
iEKPD-Ova-0262
ENSOARG00000011767.1
W5PQ88
RPS6KB2