Pan paniscus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pap-0009
ENSPPAG00000006795.1
2
iEKPD-Pap-0015
ENSPPAG00000010461.1
3
iEKPD-Pap-0099
ENSPPAG00000028449.1
4
iEKPD-Pap-0116
ENSPPAG00000029347.1
5
iEKPD-Pap-0127
ENSPPAG00000029748.1
6
iEKPD-Pap-0413
ENSPPAG00000041102.1