Pan troglodytes      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pat-0008
ENSPTRG00000000387.6
A0A2I3TPM9
RPS6KA1
2
iEKPD-Pat-0497
ENSPTRG00000052293.1
K7DQL9
RPS6KA3
3
iEKPD-Pat-0060
ENSPTRG00000003839.6
K7BI90
RPS6KA4
4
iEKPD-Pat-0412
ENSPTRG00000022064.4
A0A2I3S8A4
RPS6KA6
5
iEKPD-Pat-0171
ENSPTRG00000009477.6
H2QDK7
RPS6KB1
6
iEKPD-Pat-0066
ENSPTRG00000003957.5
H2Q486
RPS6KB2