Pelodiscus sinensis      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pes-0409
ENSPSIG00000017619.1
K7GI40
RPS6KA1
2
iEKPD-Pes-0191
ENSPSIG00000009372.1
K7FRF3
RPS6KA3
3
iEKPD-Pes-0419
ENSPSIG00000017857.1
K7GIT5
RPS6KA4
4
iEKPD-Pes-0169
ENSPSIG00000008440.1
K7FNE5
RPS6KA5
5
iEKPD-Pes-0112
ENSPSIG00000006547.1
K7FGV1
RPS6KA6
6
iEKPD-Pes-0142
ENSPSIG00000007700.1
K7FKX2
RPS6KB1
7
iEKPD-Pes-0353
ENSPSIG00000015408.1
K7GAW1
RPS6KB2