Poecilia formosa      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pof-0041
ENSPFOG00000001620.2
A0A087X8U5
2
iEKPD-Pof-0085
ENSPFOG00000003212.2
A0A087XDL2
3
iEKPD-Pof-0097
ENSPFOG00000003670.2
A0A096LW52
4
iEKPD-Pof-0149
ENSPFOG00000005547.2
A0A087XJ30
5
iEKPD-Pof-0150
ENSPFOG00000005577.1
A0A087XI36
6
iEKPD-Pof-0363
ENSPFOG00000012827.2
A0A087Y4H9
7
iEKPD-Pof-0528
ENSPFOG00000017625.1
A0A087YI90
8
iEKPD-Pof-0568
ENSPFOG00000018888.2
A0A087YLX8