Pongo abelii      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Poa-0195
ENSPPYG00000008849.1
H2NVC8
2
iEKPD-Poa-0457
ENSPPYG00000029624.1
K7EUY0
3
iEKPD-Poa-0040
ENSPPYG00000001681.2
H2N8F2
RPS6KA1
4
iEKPD-Poa-0439
ENSPPYG00000020177.2
H2PV35
RPS6KA3
5
iEKPD-Poa-0445
ENSPPYG00000020513.2
H2PW53
RPS6KA6
6
iEKPD-Poa-0193
ENSPPYG00000008807.2
H2NV94
RPS6KB1
7
iEKPD-Poa-0064
ENSPPYG00000002993.2
H2NCN4
RPS6KB2