※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (18) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Prp-0239	PRUPE_2G083600	M5XU19	PRUPE_2G083600
2		iEKPD-Prp-0274	PRUPE_2G131700	M5XIU1	PRUPE_2G131700
3		iEKPD-Prp-0513	PRUPE_3G274500	A0A251Q7J3	PRUPE_3G274500
4		iEKPD-Prp-0522	PRUPE_3G292300	M5WYG8	PRUPE_3G292300
5		iEKPD-Prp-0528	PRUPE_4G002900	M5XAC8	PRUPE_4G002900
6		iEKPD-Prp-0595	PRUPE_4G088000	M5WGF0	PRUPE_4G088000
7		iEKPD-Prp-0628	PRUPE_4G124600	A0A251PJL0	PRUPE_4G124600
8		iEKPD-Prp-0650	PRUPE_4G145600	A0A251PKQ4	PRUPE_4G145600
9		iEKPD-Prp-0776	PRUPE_5G182100	A0A251PA90	PRUPE_5G182100
10		iEKPD-Prp-0812	PRUPE_6G022800	A0A251NIW3	PRUPE_6G022800
11		iEKPD-Prp-0814	PRUPE_6G025600	M5W6Z9	PRUPE_6G025600
12		iEKPD-Prp-0842	PRUPE_6G089800	M5W762	PRUPE_6G089800
13		iEKPD-Prp-0852	PRUPE_6G122800	M5WR34	PRUPE_6G122800
14		iEKPD-Prp-0853	PRUPE_6G122900	A0A251NS09	PRUPE_6G122900
15		iEKPD-Prp-1023	PRUPE_7G114900	M5W595	PRUPE_7G114900
16		iEKPD-Prp-1080	PRUPE_7G239100	M5VQB5	PRUPE_7G239100
17		iEKPD-Prp-1145	PRUPE_8G183500	M5W298	PRUPE_8G183500
18		iEKPD-Prp-1147	PRUPE_8G193100	M5VJ17	PRUPE_8G193100