Sarcophilus harrisii      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Sah-0198
ENSSHAG00000010273.1
G3W972
2
iEKPD-Sah-0254
ENSSHAG00000012391.1
G3WGG0
RPS6KA1
3
iEKPD-Sah-0055
ENSSHAG00000003415.1
G3VL23
RPS6KA4
4
iEKPD-Sah-0308
ENSSHAG00000013938.1
G3WLS5
RPS6KA5
5
iEKPD-Sah-0283
ENSSHAG00000013276.1
G3WJH3
RPS6KA6
6
iEKPD-Sah-0366
ENSSHAG00000016073.1
G3WU29
RPS6KB1
7
iEKPD-Sah-0044
ENSSHAG00000002574.1
G3VIA5
RPS6KB2