※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (4) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Scc-0081	SPOG_03432	S9VPU1	SPOG_03432
2		iEKPD-Scc-0089	SPOG_03973	S9W203	SPOG_03973
3		iEKPD-Scc-0105	SPOG_04311	S9VTA1	SPOG_04311
4		iEKPD-Scc-0110	SPOG_04507	S9XIL7	SPOG_04507