Schizosaccharomyces pombe      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 5 genes.  Reviewed (5 or Unreviewed (0

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Scp-0042
SPAC4G8.05
Q09831
ppk14
2
iEKPD-Scp-0067
SPBC1861.09
Q9USX7
ppk22
3
iEKPD-Scp-0093
SPBC725.06c
O94324
ppk31
4
iEKPD-Scp-0105
SPCC162.10
O74426
ppk33
5
iEKPD-Scp-0114
SPCC4G3.08
Q12706
psk1