※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (29) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sem-0078	SELMODRAFT_110347
2		iEKPD-Sem-0471	SELMODRAFT_230655	D8R388	PHOT1-1
3		iEKPD-Sem-0021	SELMODRAFT_10296	D8SII4	PHOT1-2
4		iEKPD-Sem-0389	SELMODRAFT_172224	D8RKK4	PHOT2-1
5		iEKPD-Sem-0451	SELMODRAFT_186203	D8T7Q7	PHOT2-2
6		iEKPD-Sem-0020	SELMODRAFT_102667	D8RV74	SELMODRAFT_102667
7		iEKPD-Sem-0049	SELMODRAFT_106784	D8S1X3	SELMODRAFT_106784
8		iEKPD-Sem-0080	SELMODRAFT_110515	D8S7B9	SELMODRAFT_110515
9		iEKPD-Sem-0085	SELMODRAFT_110745	D8S7C4	SELMODRAFT_110745
10		iEKPD-Sem-0122	SELMODRAFT_11420	D8RT06	SELMODRAFT_11420
11		iEKPD-Sem-0134	SELMODRAFT_116886	D8SGT2	SELMODRAFT_116886
12		iEKPD-Sem-0154	SELMODRAFT_120367	D8SLZ7	SELMODRAFT_120367
13		iEKPD-Sem-0172	SELMODRAFT_124220	D8STA5	SELMODRAFT_124220
14		iEKPD-Sem-0199	SELMODRAFT_128125	D8SZ50	SELMODRAFT_128125
15		iEKPD-Sem-0201	SELMODRAFT_128234	D8SZ49	SELMODRAFT_128234
16		iEKPD-Sem-0318	SELMODRAFT_150418	D8RVW8	SELMODRAFT_150418
17		iEKPD-Sem-0439	SELMODRAFT_181752	D8SQ64	SELMODRAFT_181752
18		iEKPD-Sem-0444	SELMODRAFT_185313	D8T4F8	SELMODRAFT_185313
19		iEKPD-Sem-0446	SELMODRAFT_185762	D8T5Z2	SELMODRAFT_185762
20		iEKPD-Sem-0466	SELMODRAFT_22946	D8SCK9	SELMODRAFT_22946
21		iEKPD-Sem-0490	SELMODRAFT_234346	D8SK59	SELMODRAFT_234346
22		iEKPD-Sem-0607	SELMODRAFT_35929	D8STC8	SELMODRAFT_35929
23		iEKPD-Sem-0791	SELMODRAFT_42784	D8T1G8	SELMODRAFT_42784
24		iEKPD-Sem-0959	SELMODRAFT_62746	D8QUR3	SELMODRAFT_62746
25		iEKPD-Sem-1060	SELMODRAFT_83225	D8R2Q2	SELMODRAFT_83225
26		iEKPD-Sem-1109	SELMODRAFT_89681	D8RAV4	SELMODRAFT_89681
27		iEKPD-Sem-1130	SELMODRAFT_93137	D8RH92	SELMODRAFT_93137
28		iEKPD-Sem-1151	SELMODRAFT_98255	D8RP97	SELMODRAFT_98255
29		iEKPD-Sem-1153	SELMODRAFT_98413	D8RP88	SELMODRAFT_98413