※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (25) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sei-0813	Si025211m.g
2		iEKPD-Sei-0588	Si017186m.g	K3YSE2	LOC101756527
3		iEKPD-Sei-1343	Si040177m.g	K4AMN3	LOC101757175
4		iEKPD-Sei-0337	Si009389m.g	K3Y5A1	LOC101757498
5		iEKPD-Sei-0687	Si021263m.g	K3Z3Z5	LOC101760263
6		iEKPD-Sei-1239	Si035228m.g	K4A8M2	LOC101762974
7		iEKPD-Sei-1039	Si029340m.g	K3ZRW0	LOC101763042
8		iEKPD-Sei-1210	Si034623m.g	K4A6W8	LOC101771216
9		iEKPD-Sei-0326	Si009318m.g	K3Y530	LOC101771284
10		iEKPD-Sei-0570	Si016792m.g	K3YR98	LOC101771786
11		iEKPD-Sei-1042	Si029350m.g	K3ZRX0	LOC101772085
12		iEKPD-Sei-0466	Si013791m.g	K3YHS2	LOC101773013
13		iEKPD-Sei-0459	Si013452m.g	K3YGT4	LOC101775187
14		iEKPD-Sei-0859	Si026165m.g	K3ZHW3	LOC101775489
15		iEKPD-Sei-0371	Si010070m.g	K3Y779	LOC101776287
16		iEKPD-Sei-0741	Si021826m.g	K3Z5K8	LOC101777825
17		iEKPD-Sei-0623	Si019239m.g	K3YY89	LOC101779394
18		iEKPD-Sei-0324	Si009308m.g	K3Y520	LOC101780476
19		iEKPD-Sei-0100	Si001204m.g	K3XH33	LOC101780702
20		iEKPD-Sei-0836	Si025927m.g	K3ZH75	LOC101781435
21		iEKPD-Sei-0243	Si006122m.g	K3XW14	LOC101783223
22		iEKPD-Sei-1016	Si029122m.g	K3ZR90	LOC101784376
23		iEKPD-Sei-0866	Si026261m.g	K3ZI59	LOC101785206
24		iEKPD-Sei-0385	Si010766m.g	K3Y974	SETIT_010766mg
25		iEKPD-Sei-1337	Si039958m.g	A0A0Q3QII3	SETIT_039958mg