Sorex araneus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Soa-0205
ENSSARG00000008834.1
2
iEKPD-Soa-0290
ENSSARG00000012705.1
3
iEKPD-Soa-0293
ENSSARG00000012753.1
4
iEKPD-Soa-0301
ENSSARG00000013142.1
5
iEKPD-Soa-0306
ENSSARG00000013439.1
6
iEKPD-Soa-0308
ENSSARG00000013531.1