Takifugu rubripes      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Tar-0107
ENSTRUG00000003821.1
H2S9D2
LOC101062507
2
iEKPD-Tar-0024
ENSTRUG00000000759.1
H2RNW3
LOC101062814
3
iEKPD-Tar-0272
ENSTRUG00000008385.1
H2T8K6
LOC101069154
4
iEKPD-Tar-0016
ENSTRUG00000000567.1
H2RMH8
LOC101073756
5
iEKPD-Tar-0177
ENSTRUG00000005648.1
H2SML4
LOC101074350
6
iEKPD-Tar-0354
ENSTRUG00000010729.1
H2TQW4
rps6ka1
7
iEKPD-Tar-0189
ENSTRUG00000005953.1
H2SPZ0
rps6ka3
8
iEKPD-Tar-0379
ENSTRUG00000011435.1
H2TW14
rps6ka5