Tetraodon nigroviridis      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ten-0081
ENSTNIG00000003337.1
H3CCF1
2
iEKPD-Ten-0341
ENSTNIG00000011636.1
H3D250
3
iEKPD-Ten-0408
ENSTNIG00000013802.1
H3D8G3
4
iEKPD-Ten-0503
ENSTNIG00000016170.1
H3DFG7
5
iEKPD-Ten-0544
ENSTNIG00000017266.1
H3DIR0
6
iEKPD-Ten-0562
ENSTNIG00000017798.1
H3DKA4
7
iEKPD-Ten-0609
ENSTNIG00000019285.1
H3DPN8