※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (19) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tru-0557	TRIUR3_11556	T1M288
2		iEKPD-Tru-0989	TRIUR3_21915	M7ZY95	4327129
3		iEKPD-Tru-0280	TRIUR3_05193	M7Z0V6	TRIUR3_05193
4		iEKPD-Tru-0366	TRIUR3_06815	M8B5J4	TRIUR3_06815
5		iEKPD-Tru-0474	TRIUR3_09580	M7YJS4	TRIUR3_09580
6		iEKPD-Tru-0512	TRIUR3_10443	M7YG84	TRIUR3_10443
7		iEKPD-Tru-0656	TRIUR3_13772	M7YJB1	TRIUR3_13772
8		iEKPD-Tru-0705	TRIUR3_14910	M8AKM7	TRIUR3_14910
9		iEKPD-Tru-0733	TRIUR3_15657	M7ZTX5	TRIUR3_15657
10		iEKPD-Tru-0763	TRIUR3_16259	M7YNI9	TRIUR3_16259
11		iEKPD-Tru-0825	TRIUR3_18097	M7ZI69	TRIUR3_18097
12		iEKPD-Tru-0943	TRIUR3_20751	M7ZC23	TRIUR3_20751
13		iEKPD-Tru-0965	TRIUR3_21379	M7YHL6	TRIUR3_21379
14		iEKPD-Tru-1040	TRIUR3_23226	M7YN91	TRIUR3_23226
15		iEKPD-Tru-1268	TRIUR3_30380	M7YES1	TRIUR3_30380
16		iEKPD-Tru-1384	TRIUR3_33603	M7ZQT7	TRIUR3_33603
17		iEKPD-Tru-1388	TRIUR3_33718	M7YUA4	TRIUR3_33718
18		iEKPD-Tru-1422	TRIUR3_34615	M8A087	TRIUR3_34615
19		iEKPD-Tru-1429	TRIUR3_34731	M8ARH6	TRIUR3_34731